Senior Scientist - Histology of respiratory diseases | AstraZeneca | Göteborg

Are you an experienced scientist ready to apply your skills in a diverse and dynamic company? If you can envision providing scientific expertise in a role that can impact patients’ lives – join us now!

Brief information about the assignment:

We are now looking to recruit a Senior Scientist experienced in histology with a background in image analysis and ideally experience with pathological assessment of respiratory diseases. If you have a drive for innovation and idea generation as well as excellent laboratory skills, this is a great opportunity to join the Bioscience Department within Immunology. The role is located at our vibrant R&D site in Gothenburg, Sweden.

Location: Gothenburg (Mölndal)
Type of employment: Consultant assignment
Assignment duration: 6 month, with the possibility of extension

About the role

As a Senior Scientist you will be a vital member of the department and in various working teams to progress our respiratory and immunological drug discovery projects. You will actively take part in scientific discussions, gain input from others and be involved in multiple project meetings to present and discuss experimental plans and data.

This is a partly lab-based role where you will be actively involved in experimental phase of histological analyses, with responsibility to coordinate, perform and evaluate experiments as well as drive the establishment of new techniques. Characterization and validation of target expression and subsequent evaluation of engagement of the target by drug treatment in both patient and in vivo tissue samples will be key areas of your daily work. You will independently assess and report data with a clear understanding of its reliability, interpretation of findings and draw appropriate conclusions with input from others.

About you

We are looking for a team player with strong background in histology and related image analysis techniques with a specific focus on respiratory diseases, ideally complemented by some experience in pathology and pre-clinical drug discovery processes.

Essential for the role:

• PhD in a relevant discipline (area of Bioscience/Respiratory) ideally complemented with experience of working in a drug discovery environment
• Strong experimental histology skills in performing immunohistochemistry, histochemistry, in situ hybridization (including RNAscope) with automated machines (e.g. Ventana Discovery Ultra and Leica Bond)
• Proven knowledge and experience in image analysis platforms (e.g. Visiopharm and Halo)
• Understanding of statistical methods, quality control and data reporting/archiving
• Excellent written and oral communication skills, including presentation skills. You are organized and incorporate the views of others in your communication and collaboration

Desirable for the role:

• Knowledge of respiratory diseases, including target and mechanism knowledge and basic understanding of pharmacokinetics

• Knowledge in histology scoring and histomorphometry
• Good understanding of pharmacology, physiology and immunology
• Familiarity with deep learning image analysis methods, e.g. image segmentation and classification
• Practical experience with a scripting language (Phyton, R) modelling tool
• Knowledge in advanced histological techniques such as spatial transcriptomics, hyperflex staining and tissue optical clearing

• Be respectful, communicate openly and show effective collaborative behavior to obtain high quality study results

As one of us

As an employed staffing consultant at Lernia, you will always receive a competitive salary, vacation benefits, pension contributions, insurance coverage, and be part of our collective agreement. We care about your well-being, which is why we offer all our consultants wellness allowances and access to occupational health services. During your employment, you will have a dedicated consultant manager responsible for your assignment, ensuring you thrive at your workplace while supporting and developing you in your professional role.

How to Apply

To apply for this position, click on the "Apply" link above and fill out the form. For any questions or inquiries, please contact hampus.svensson@lernia.se. We conduct interviews on an ongoing basis, so please submit your application as soon as possible.